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There are 8 ways to get from Mestre to Rome by train, bus, night train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  3h 33m

  1. Take the train from Venezia Mestre to Roma Termini Fr / ...

$40 - $85

Cheapest option

Bus  •  6h 20m

  1. Take the bus from Venice, Venice Mestre to Rome, Rome Tiburtina Bus station N533 / ...

$17 - $50

6 alternative options

Night train  •  7h 54m

  1. Take the night train from Venezia Mestre to Roma Termini Icn

$55 - $75

Drive  •  4h 55m

  1. Drive from Mestre to Rome 325.1 miles

$75 - $120

Fly from Venice  •  3h 7m

  1. Fly from Venice (VCE) to Rome (FCO) VCE - FCO

$48 - $251

Train to Trieste, fly  •  4h 16m

  1. Take the train from Venezia Mestre to Trieste Aeroporto
  2. Fly from Trieste (TRS) to Rome (FCO) TRS - FCO

$70 - $276

Train to Verona, fly  •  5h 11m

  1. Take the train from Venezia Mestre to Verona Porta Nuova
  2. Fly from Verona (VRN) to Rome (FCO) VRN - FCO

$56 - $320

Train to Bologna, fly  •  5h 10m

  1. Take the train from Venezia Mestre to Bologna C.Le
  2. Fly from Bologna (BLQ) to Rome (FCO) BLQ - FCO

$68 - $306

Questions & Answers

The cheapest way to get from Mestre to Rome is to bus which costs 15€ - 45€ and takes 6h 20m.

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The quickest way to get from Mestre to Rome is to fly which costs 40€ - 220€ and takes 3h 7m.

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Yes, there is a direct bus departing from Venice, Venice Mestre and arriving at Rome, Rome Tiburtina Bus station station. Services depart once daily, and operate every day. The journey takes approximately 6h 20m.

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Yes, there is a direct train departing from Venezia Mestre and arriving at Roma Termini. Services depart hourly, and operate every day. The journey takes approximately 3h 33m.

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The distance between Mestre and Rome is 400 km. The road distance is 520.1 km.

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The best way to get from Mestre to Rome without a car is to train which takes 3h 33m and costs 35€ - 75€.

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The train from Venezia Mestre to Roma Termini takes 3h 33m including transfers and departs hourly.

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Mestre to Rome bus services, operated by FlixBus, depart from Venice, Venice Mestre station.

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Mestre to Rome train services, operated by Trenitalia Frecce, depart from Venezia Mestre station.

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The best way to get from Mestre to Rome is to train which takes 3h 33m and costs 35€ - 75€. Alternatively, you can bus, which costs 15€ - 45€ and takes 6h 20m, you could also fly, which costs 40€ - 220€ and takes 3h 7m.

Mode details

Map of how to get from Mestre to Rome.
Launch map view
  • Distance: 249.8 miles
  • Duration: 3h 33m

What companies run services between Mestre, Italy and Rome, Italy?

Trenitalia Frecce operates a train from Mestre to Rome hourly. Tickets cost $55 - $85 and the journey takes 3h 33m. ItaloTreno also services this route every 4 hours. Alternatively, FlixBus operates a bus from Mestre to Rome twice daily. Tickets cost $29 - $50 and the journey takes 6h 20m. RegioJet also services this route 3 times a week.

Airlines
Alitalia
Website
alitalia.com
Flights from Venice to Rome
Ave. Duration
1h 5m
When
Every day
Estimated price
$40 - $290
Flights from Trieste to Rome
Ave. Duration
1h 5m
When
Every day
Estimated price
$75 - $360
Flights from Verona to Rome
Ave. Duration
1h
When
Every day
Estimated price
$30 - $370
Flights from Bologna to Rome
Ave. Duration
1h
When
Every day
Estimated price
$65 - $350
Neos
Website
neosair.it
Flights from Verona to Rome
Ave. Duration
1h 3m
When
Wednesday, Thursday and Sunday
Estimated price
$80 - $600
Flights from Bologna to Rome
Ave. Duration
1h
When
Wednesday
Estimated price
$70 - $600
Train operators
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Venezia Mestre to Roma Termini
Ave. Duration
3h 33m
Frequency
Hourly
Estimated price
$55 - $85
Website
orario.trenitalia.com
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Venezia Mestre Station to Roma Termini Station
Ave. Duration
3h 33m
Frequency
Every 4 hours
Estimated price
$40 - $60
Website
italotreno.it
Train from Venezia Mestre to Verona Porta Nuova
Ave. Duration
57m
Frequency
Every 4 hours
Estimated price
$18 - $26
Website
italotreno.it
Train from Venezia Mestre Station to Bologna Centrale Station
Ave. Duration
1h 15m
Frequency
Every 4 hours
Estimated price
$21 - $30
Website
italotreno.it
Trenitalia Intercity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Night train from Venezia Mestre to Roma Termini
Ave. Duration
7h 54m
Frequency
Once daily
Estimated price
$55 - $75
Website
orario.trenitalia.com
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Venezia Mestre to Trieste Aeroporto
Ave. Duration
1h 23m
Frequency
Hourly
Estimated price
$8 - $19
Website
orario.trenitalia.com
1st Class
$15 - $19
Train from Venezia Mestre to Verona Porta Nuova
Ave. Duration
2h 3m
Frequency
Hourly
Estimated price
$8 - $19
Website
orario.trenitalia.com
1st Class
$15 - $19
Train from Venezia Mestre to Bologna C.Le
Ave. Duration
1h 51m
Frequency
Hourly
Estimated price
$11 - $24
Website
orario.trenitalia.com
1st Class
$20 - $24
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Venice, Venice Mestre to Rome, Rome Tiburtina Bus station
Ave. Duration
6h 20m
Frequency
Twice daily
Estimated price
$29 - $50
Website
flixbus.co.uk
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.com
Bus from Venice Mestre, St. di autobus to Rome, Largo Mazzoni
Ave. Duration
8h 5m
Frequency
3 times a week
Estimated price
$17 - $22
Website
regiojet.com

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Venice Airport to Rome Airport is the direct flight which takes 1h 5m.

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Mestre to Rome bus services, operated by FlixBus, arrive at Rome, Rome Tiburtina Bus station.

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Mestre to Rome train services, operated by Trenitalia Frecce, arrive at Roma Termini station.

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Yes, the driving distance between Mestre to Rome is 520 km. It takes approximately 4h 55m to drive from Mestre to Rome.

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Alitalia offers flights from Venice Airport to Rome Airport.

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Book your Mestre to Rome train tickets online with Rome2rio.

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Book your Mestre to Rome bus tickets online with Distribusion.

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There are 12050+ hotels available in Rome. Prices start at $51 USD per night.

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The best way to get from Mestre to Venice Airport is to bus which takes 20m and costs 1€ - 4€.

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