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There are 7 ways to get from Buffalo to Chicago by plane, train, bus, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Buffalo to Chicago Midway  •  3h 37m

  1. Fly from Buffalo (BUF) to Chicago Midway (MDW) BUF - MDW

$134 - $406

Cheapest option

Bus  •  16h 5m

  1. Take the bus from Buffalo, NY - 181 Ellicott Street to Toronto, ON - 610 Bay Street Ny / ...
  2. Take the bus from Toronto, ON - 610 Bay Street to Chicago, IL - Amtrack Station Toronto

$59 - $156

5 alternative options

Fly Buffalo to Chicago O'Hare  •  4h 8m

  1. Fly from Buffalo (BUF) to Chicago O'Hare (ORD) BUF - ORD

$124 - $377

Train to Rochester, fly to Chicago O'Hare  •  5h 59m

  1. Take the train from Buffalo Amtrak Station to Rochester Amtrak Station
  2. Fly from Rochester (ROC) to Chicago O'Hare (ORD) ROC - ORD

$169 - $409

Train  •  11h 44m

  1. Take the train from Buffalo Depew Station to Chicago Union Station Lake Shore Limited

$94 - $251

Bus, night bus  •  16h 5m

  1. Take the bus from Buffalo, NY - 181 Ellicott Street to Toronto, ON - 610 Bay Street Ny / ...
  2. Take the night bus from Toronto, On to Chicago Amtrak, Il 5531

$64 - $166

Drive  •  8h 55m

  1. Drive from Buffalo to Chicago 535.9 miles

$50 - $80

Questions & Answers

The cheapest way to get from Buffalo to Chicago is to drive which costs $50 - $80 and takes 8h 55m.

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The quickest way to get from Buffalo to Chicago is to fly which costs $130 - $410 and takes 3h 37m.

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No, there is no direct bus from Buffalo to Chicago station. However, there are services departing from Buffalo, NY - 181 Ellicott Street and arriving at Chicago, IL - Amtrack Station via Toronto, ON - 610 Bay Street. The journey, including transfers, takes approximately 16h 5m.

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No, there is no direct train from Buffalo station to Chicago station. However, there are services departing from Buffalo Amtrak Station and arriving at Chicago Union Station via Buffalo Depew Station. The journey, including transfers, takes approximately 11h 44m.

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The distance between Buffalo and Chicago is 454 miles. The road distance is 535.9 miles.

Get driving directions

The best way to get from Buffalo to Chicago without a car is to train which takes 11h 44m and costs $90 - $260.

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It takes approximately 3h 37m to get from Buffalo to Chicago, including transfers.

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Buffalo to Chicago bus services, operated by Greyhound Canada, depart from Buffalo, NY - 181 Ellicott Street station.

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Buffalo to Chicago train services, operated by Amtrak, arrive at Buffalo Depew Station.

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The best way to get from Buffalo to Chicago is to fly which takes 3h 37m and costs $130 - $410. Alternatively, you can train, which costs $90 - $260 and takes 11h 44m, you could also bus, which costs $55 - $160 and takes 16h 5m.

Mode details

Map of how to get from Buffalo to Chicago.
Launch map view
  • Distance: 454.4 miles
  • Duration: 3h 37m

What companies run services between Buffalo, NY, USA and Chicago, IL, USA?

Southwest Airlines and Delta fly from Buffalo to Chicago 4 times a day. Alternatively, Amtrak operates a train from Buffalo to Chicago twice daily. Tickets cost $75 - $220 and the journey takes 10h 30m.

Airlines
United Airlines
Website
united.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
2h 5m
When
Every day
Estimated price
$140 - $750
Flights from Buffalo to Chicago O'Hare via Washington Dulles
Ave. Duration
4h 31m
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $750
Flights from Rochester to Chicago O'Hare
Ave. Duration
2h 9m
When
Every day
Estimated price
$180 - $700
Flights from Rochester to Chicago O'Hare via Washington Dulles
Ave. Duration
4h 31m
When
Every day
Estimated price
$180 - $700
American Airlines
Website
aa.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
2h 6m
When
Every day
Estimated price
$120 - $650
Flights from Buffalo to Chicago O'Hare via Philadelphia
Ave. Duration
4h 47m
When
Every day
Estimated price
$120 - $650
Flights from Buffalo to Chicago O'Hare via Reagan Washington
Ave. Duration
4h 58m
When
Every day
Estimated price
$120 - $650
Flights from Rochester to Chicago O'Hare
Ave. Duration
2h 10m
When
Every day
Estimated price
$160 - $700
Flights from Rochester to Chicago O'Hare via Philadelphia
Ave. Duration
4h 51m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $700
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Chicago Midway
Ave. Duration
1h 49m
When
Every day
Estimated price
$160 - $750
Flights from Buffalo to Chicago Midway via Baltimore
Ave. Duration
4h 10m
When
Saturday
Estimated price
$160 - $750
Delta
Website
delta.com
Flights from Buffalo to Chicago Midway via Detroit
Ave. Duration
4h 5m
When
Monday to Saturday
Estimated price
$130 - $800
Flights from Buffalo to Chicago O'Hare via Detroit
Ave. Duration
4h 12m
When
Every day
Estimated price
$130 - $800
Flights from Rochester to Chicago O'Hare via Detroit
Ave. Duration
4h 11m
When
Every day
Estimated price
$160 - $800
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Buffalo Amtrak Station to Rochester Amtrak Station
Ave. Duration
1h 8m
Frequency
3 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Train from Buffalo Depew Station to Chicago Union Station
Ave. Duration
10h 30m
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Buffalo to Rochester
Ave. Duration
1h 8m
Frequency
Once daily
Estimated price
$40 - $85
Website
viarail.ca
Escape
$19 - $40
Economy
$40 - $55
EconomyPlus
$55 - $85
Business
$55 - $80
Bus operators
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Buffalo, NY - 181 Ellicott Street to Toronto, ON - 610 Bay Street
Ave. Duration
2h 30m
Frequency
Every 4 hours
Estimated price
$14 - $40
Website
Greyhound.ca
Advanced Purchase
$14 - $21
Online Fare
$16 - $35
Standard Fare
$25 - $40
Refundable
$29 - $45
Bus from Toronto, ON - 610 Bay Street to Chicago, IL - Amtrack Station
Ave. Duration
12h 35m
Frequency
Once daily
Estimated price
$45 - $120
Website
Greyhound.ca
Advanced Purchase
$45 - $70
Online Fare
$60 - $90
Standard Fare
$75 - $120
Refundable
$85 - $130
Megabus Canada
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Buffalo, Ny to Toronto, On
Ave. Duration
2h 45m
Frequency
4 times a day
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Night bus from Toronto, On to Chicago Amtrak, Il
Ave. Duration
12h 35m
Frequency
Once daily
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $85
Flexible
$100 - $130

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Buffalo Airport to Chicago Midway Airport is the direct flight which takes 1h 45m.

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Buffalo to Chicago bus services, operated by Greyhound Canada, arrive at Chicago, IL - Amtrack Station.

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Chicago is 1h behind Buffalo. It is currently 3:02 AM in Buffalo and 2:02 AM in Chicago.

Buffalo to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.

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Yes, the driving distance between Buffalo to Chicago is 536 miles. It takes approximately 8h 55m to drive from Buffalo to Chicago.

Get driving directions

Delta and Southwest Airlines offer flights from Buffalo Airport to Chicago Midway Airport.

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Book your Buffalo to Chicago train tickets online with Rome2rio.

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Book your Buffalo to Chicago bus tickets online with Busbud and Busbud.

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There are 763+ hotels available in Chicago. Prices start at $75 USD per night.

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The best way to get from Buffalo to Buffalo Airport is to line 204 bus which takes 17m and costs $2.

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