The average train between Vesoul and Lyon takes 4h 10m and the fastest train takes 3h 18m. The train service runs several times per day from Vesoul to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Vesoul and Lyon. The earliest departure is at 6:23 AM in the morning, and the last departure from Vesoul is at 7:01 PM which arrives into Lyon at 10:52 PM. All services require a transfer at Culmont Chalindrey and take an average of 4h 10m. The schedules shown below are for the next available departures.


5h 21m • 2 changes


3h 18m • 2 changes


4h 4m • 2 changes


4h 16m • 2 changes


5h 21m • 2 changes


3h 18m • 2 changes


4h 4m • 2 changes


4h 16m • 2 changes


5h 21m • 2 changes


3h 18m • 2 changes


4h 4m • 2 changes


4h 16m • 2 changes


5h 21m • 2 changes


3h 18m • 2 changes


4h • 2 changes


4h 16m • 2 changes
Want to know about travelling from Vesoul to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Vesoul to Lyon. However, there are services departing from Vesoul station and arriving at Lyon station via Culmont Chalindrey. The journey, including transfers, takes approximately 4h 10m.
Vesoul to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Vesoul station.
Vesoul to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Lyon Part Dieu station.
Book your Vesoul to Lyon train tickets online with Société Nationale des Chemins de fer Français (SNCF).
The distance between Vesoul and Lyon is 231 km. The road distance is 338 km.
You can take a train from Vesoul to Lyon Part Dieu via Culmont Chalindrey and Dijon Ville in around 4h 41m.