The average train between Times Square and Natick takes 5h 17m and the fastest train takes 4h 18m. There is a train service every few hours from Times Square to Natick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Times Square and Natick. The earliest departure is at 5:27 AM in the morning, and the last departure from Times Square is at 9:29 PM which arrives into Natick at 5:40 AM. All services require a transfer at Boston and take an average of 5h 17m. The schedules shown below are for the next available departures.

5h 3m • 1 change

5h 46m • 1 change

4h 33m • 1 change

4h 28m • 1 change

5h 3m • 1 change

5h 46m • 1 change

4h 33m • 1 change

4h 28m • 1 change

5h 3m • 1 change

5h 46m • 1 change

4h 33m • 1 change

4h 28m • 1 change

5h 56m • 1 change

6h 40m • 1 change

4h 29m • 1 change

5h 26m • 1 change

5h 56m • 1 change

5h 20m • 1 change

4h 29m • 1 change

5h 42m • 1 change
Want to know about travelling from Times Square to Natick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Times Square to Natick. However, there are services departing from Times Square station and arriving at Natick station via Boston. The journey, including transfers, takes approximately 5h 17m.
Times Square to Natick train services, operated by Amtrak Northeast Regional, depart from Ny Moynihan Train Hall At Penn Station.
Times Square to Natick train services, operated by Amtrak Northeast Regional, arrive at Boston station.
The distance between Times Square and Natick is 277.5 km. The road distance is 397 km.
Amtrak Acela operates a train from Ny Moynihan Train Hall At Penn Station to Boston every 4 hours. Tickets cost $50–750 and the journey takes 3h 44m. Amtrak Northeast Regional also services this route every 3 hours.