The average train between Times Square and Natick takes 5h 36m and the fastest train takes 4h 29m. There is a train service every few hours from Times Square to Natick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Times Square and Natick. The earliest departure is at 5:27 AM in the morning, and the last departure from Times Square is at 7:50 PM which arrives into Natick at 5:42 AM. All services require a transfer at Boston and take an average of 5h 36m. The schedules shown below are for the next available departures.

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Want to know about travelling from Times Square to Natick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Times Square to Natick. However, there are services departing from Times Square station and arriving at Natick station via Boston. The journey, including transfers, takes approximately 5h 36m.
Times Square to Natick train services, operated by Amtrak Acela, depart from Ny Moynihan Train Hall At Penn Station.
Times Square to Natick train services, operated by Amtrak Acela, arrive at Boston station.
The distance between Times Square and Natick is 277.5 km. The road distance is 397 km.
Amtrak Acela operates a train from Ny Moynihan Train Hall At Penn Station to Boston every 4 hours. Tickets cost $50–750 and the journey takes 3h 36m. Amtrak also services this route every 3 hours.