The average train between Slough and Marylebone takes 37 min and the fastest train takes 23 min. The train runs at least 3 times per hour from Slough to Marylebone. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 20 minutes between Slough and Marylebone. The earliest departure is at 4:59 AM at night, and the last departure from Slough is at 11:42 PM which arrives into Marylebone at 12:27 AM. All services require a transfer at London Paddington and take an average of 37 min. The schedules shown below are for the next available departures.

40 min • 1 change
Arrives next day

35 min • 1 change
Arrives next day

45 min • 1 change

41 min • 1 change

42 min • 1 change

28 min • 1 change

42 min • 1 change

50 min • 1 change

41 min • 1 change

41 min • 1 change

33 min • 1 change
Want to know about travelling from Slough to Marylebone? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Marylebone. However, there are services departing from Slough station and arriving at Marylebone station via London Paddington. The journey, including transfers, takes approximately 37 min.
Slough to Marylebone train services, operated by Great Western Railway (GWR), depart from Slough station.
Slough to Marylebone train services, operated by Great Western Railway (GWR), arrive at London Paddington station.
Book your Slough to Marylebone train tickets online with Great Western Railway (GWR), London Underground (Tube) and Elizabeth Line (TfL).
The distance between Slough and Marylebone is 30.5 km. The road distance is 31 km.
Great Western Railway (GWR) operates a train from Slough to London Paddington every 30 minutes. Tickets cost £8–16 and the journey takes 21 min. Elizabeth Line (TfL) also services this route every 30 minutes.