The average train between Slough and Lyon takes 7h 27m and the fastest train takes 6h 2m. The train service runs several times per day from Slough to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Slough and Lyon. The earliest departure is at 6:08 AM in the morning, and the last departure from Slough is at 11:21 PM which arrives into Lyon at 12:10 PM. All services require a transfer at Farringdon Without and take an average of 7h 27m. The schedules shown below are for the next available departures.




7h 14m • 4 changes
Arrives next day




13h 43m • 4 changes
Arrives next day




12h 49m • 4 changes




7h 2m • 4 changes




7h 3m • 4 changes




7h 34m • 4 changes




7h 13m • 4 changes




7h 2m • 4 changes




7h 3m • 4 changes




7h 34m • 4 changes




7h 13m • 4 changes




7h 2m • 4 changes




7h 3m • 4 changes




7h 34m • 4 changes




7h 13m • 4 changes




7h 2m • 4 changes




7h 3m • 4 changes




7h 34m • 4 changes




7h 13m • 4 changes
Want to know about travelling from Slough to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Lyon. However, there are services departing from Slough station and arriving at Lyon station via Paris Nord. The journey, including transfers, takes approximately 7h 27m.
Slough to Lyon train services, operated by Elizabeth Line (TfL), depart from London St Pancras Intl station.
Slough to Lyon train services, operated by Elizabeth Line (TfL), arrive at Lyon Perrache station.
Book your Slough to Lyon train tickets online with Elizabeth Line (TfL), Thameslink and 4 other operators.
The distance between Slough and Lyon is 754.7 km. The road distance is 924 km.
You can take a train from Slough to Lyon Perrache via Farringdon Without, Farringdon, London St Pancras Intl, Paris Nord, and Paris Gare De Lyon in around 6h 19m.