The average train between Sistine Chapel and Pisa takes 3h 44m and the fastest train takes 3h 9m. The train service runs several times per day from Sistine Chapel to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Sistine Chapel and Pisa. The earliest departure is at 6:20 AM in the morning, and the last departure from Sistine Chapel is at 8:03 PM which arrives into Pisa at 12:25 AM. All services require a transfer at Roma S. Pietro and take an average of 3h 44m. The schedules shown below are for the next available departures.

3h 25m • 1 change

4h 10m • 1 change

4h 3m • 1 change

3h 32m • 1 change

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4h 12m • 1 change

4h 13m • 1 change

3h 32m • 1 change

3h 25m • 1 change

4h 12m • 1 change

4h 13m • 1 change

3h 32m • 1 change

3h 25m • 1 change

4h 12m • 1 change

4h 13m • 1 change

3h 32m • 1 change

3h 25m • 1 change

4h 12m • 1 change

4h 13m • 1 change

3h 32m • 1 change
Want to know about travelling from Sistine Chapel to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sistine Chapel to Pisa. However, there are services departing from Sistine Chapel station and arriving at Pisa station via Civitavecchia. The journey, including transfers, takes approximately 3h 44m.
Sistine Chapel to Pisa train services, operated by Trenitalia Intercity, depart from Roma S. Pietro station.
Sistine Chapel to Pisa train services, operated by Trenitalia Intercity, arrive at Pisa Centrale station.
Book your Sistine Chapel to Pisa train tickets online with Trenitalia Intercity, Trenitalia and Trenitalia Frecce.
The distance between Sistine Chapel and Pisa is 261.3 km. The road distance is 321 km.
You can take a vehicle from Sistine Chapel to Pisa Centrale via Roma S. Pietro and Civitavecchia in around 3h 42m.