Train Siena to Genoa from €44 | Tickets & Timetables

Trip Overview

The average train between Siena and Genoa takes 4h 49m and the fastest train takes 4h. The train service runs several times per day from Siena to Genoa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 49m
Duration: 268 km
Distance: €44
Average price: Every 2 hours
Frequency

Train (Trenitalia)

best

Take the train from Siena to Empolitrain Re
Take the train from Empoli to Pisa Centraletrain Re
Take the train from Pisa Centrale to Genova Brignoletrain Fb / ...

4h 54m

€30–68

Siena to Genoa train times

Trains run every 2 hours between Siena and Genoa. The earliest departure is at 6:36 AM in the morning, and the last departure from Siena is at 9:40 PM which arrives into Genoa at 8:07 AM. All services require a transfer at Empoli and take an average of 4h 49m. The schedules shown below are for the next available departures.

Departing Thursday, April 30, 2026

4:41 PM → 8:54 PM
4h 13m • 2 changes
5:41 PM → 10:06 PM
4h 25m • 2 changes
7:18 PM → 11:28 PM
4h 10m • 2 changes
8:18 PM → 12:47 AM
Arrives next day
4h 29m • 2 changes
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Departing Friday, May 1, 2026

6:36 AM → 10:55 AM
4h 19m • 2 changes
7:15 AM → 11:45 AM
4h 30m • 2 changes
8:48 AM → 2:07 PM
5h 19m • 2 changes
11:45 AM → 4:06 PM
4h 21m • 2 changes
Show more

Departing Saturday, May 2, 2026

6:36 AM → 10:55 AM
4h 19m • 2 changes
7:33 AM → 11:45 AM
4h 12m • 2 changes
9:18 AM → 2:07 PM
4h 49m • 2 changes
10:41 AM → 3:26 PM
4h 45m • 2 changes
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Departing Sunday, May 3, 2026

6:36 AM → 10:55 AM
4h 19m • 2 changes
7:15 AM → 11:45 AM
4h 30m • 2 changes
8:48 AM → 2:07 PM
5h 19m • 2 changes
11:45 AM → 4:06 PM
4h 21m • 2 changes
Show more

Departing Monday, May 4, 2026

6:36 AM → 10:55 AM
4h 19m • 2 changes
7:33 AM → 11:45 AM
4h 12m • 2 changes
11:45 AM → 4:06 PM
4h 21m • 2 changes
12:41 PM → 4:55 PM
4h 14m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Siena to Genoa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.