The average train between Siena and Brussels takes 18h 44m and the fastest train takes 14h 32m. The train service runs several times per day from Siena to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Siena and Brussels. The earliest departure is at 7:02 AM in the morning, and the last departure from Siena is at 6:18 PM which arrives into Brussels at 3:44 PM. All services require a transfer at Firenze S.M.N. and take an average of 18h 44m. The schedules shown below are for the next available departures.




14h 32m • 4 changes
Arrives next day




20h 26m • 4 changes
Arrives next day




21h 26m • 4 changes




14h 32m • 4 changes
Arrives next day




20h 26m • 4 changes
Arrives next day




21h 26m • 4 changes
Want to know about travelling from Siena to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Siena to Brussels. However, there are services departing from Siena station and arriving at Brussels station via Firenze S.M.N.. The journey, including transfers, takes approximately 18h 44m.
Siena to Brussels train services, operated by Trenitalia, depart from Siena station.
Siena to Brussels train services, operated by Trenitalia, arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Siena to Brussels train tickets online with Trenitalia, Trenitalia Frecce and 3 other operators.
The distance between Siena and Brussels is 989.4 km. The road distance is 1,566 km.
You can take a train from Siena to Brussel-Zuid / Bruxelles-Midi via Firenze S.M.N., Torino Porta Susa, Paris Gare de Lyon, and Paris Nord in around 13h 15m.