The average train between Rome and Trepuzzi takes 6h 32m and the fastest train takes 6h 18m. The train service runs several times per day from Rome to Trepuzzi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Rome and Trepuzzi. The earliest departure is at 8:00 AM in the morning, and the last departure from Rome is at 6:05 PM which arrives into Trepuzzi at 12:44 AM. All services require a transfer, and take on average 6h 32m. The schedules shown below are for the next available departures.

6h 33m • 1 change

6h 35m • 1 change

6h 18m • 1 change
Arrives next day

6h 39m • 1 change

6h 33m • 1 change

6h 35m • 1 change

6h 18m • 1 change
Arrives next day

6h 39m • 1 change

6h 33m • 1 change

6h 35m • 1 change

6h 18m • 1 change
Arrives next day

6h 39m • 1 change

6h 23m • 1 change

6h 35m • 1 change

6h 25m • 1 change
Arrives next day

6h 39m • 1 change

7h 18m • 1 change

6h 23m • 1 change

6h 35m • 1 change

6h 25m • 1 change
Want to know about travelling from Rome to Trepuzzi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Trepuzzi. However, there are services departing from Rome station and arriving at Trepuzzi station via Brindisi. The journey, including transfers, takes approximately 6h 32m.
Rome to Trepuzzi train services, operated by Trenitalia Frecce, depart from Roma Termini station.
Rome to Trepuzzi train services, operated by Trenitalia Frecce, arrive at Brindisi station.
Book your Rome to Trepuzzi train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Rome and Trepuzzi is 495 km. The road distance is 616 km.
Trenitalia Frecce operates a train from Roma Termini to Brindisi 5 times a day. Tickets cost €85–170 and the journey takes 5h 23m.