The average train between Rome and Segrate takes 4h 3m and the fastest train takes 3h 37m. There is a train service every few hours from Rome to Segrate. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Rome and Segrate. The earliest departure is at 5:40 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Segrate at 11:47 PM. All services require a transfer at Milano Rogoredo and take an average of 4h 3m. The schedules shown below are for the next available departures.

4h 22m • 1 change

4h 19m • 1 change

4h 22m • 1 change

3h 37m • 1 change

4h 22m • 1 change

3h 47m • 1 change

4h 22m • 1 change

4h 19m • 1 change

4h 22m • 1 change

3h 47m • 1 change

4h 22m • 1 change

4h 19m • 1 change

4h 22m • 1 change

3h 47m • 1 change

4h 22m • 1 change

4h 19m • 1 change
Want to know about travelling from Rome to Segrate? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Segrate. However, there are services departing from Rome station and arriving at Segrate station via Milano Rogoredo. The journey, including transfers, takes approximately 4h 3m.
Rome to Segrate train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Segrate train services, operated by ItaloTreno, arrive at Milano Rogoredo station.
The distance between Rome and Segrate is 475 km. The road distance is 591 km.
ItaloTreno operates a train from Roma Termini to Milano Rogoredo hourly. Tickets cost €70–150 and the journey takes 2h 54m.