The average train between Rome and Segrate takes 4h 6m and the fastest train takes 3h 37m. There is a train service every few hours from Rome to Segrate. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Rome and Segrate. The earliest departure is at 5:35 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Segrate at 11:49 PM. All services require a transfer at Milano Rogoredo and take an average of 4h 6m. The schedules shown below are for the next available departures.

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4h 22m • 1 changeWant to know about travelling from Rome to Segrate? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Segrate. However, there are services departing from Roma Termini station and arriving at Milano Rogoredo station via Milano Rogoredo station. The journey, including transfers, takes approximately 4h 6m.
Rome to Segrate train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Segrate train services, operated by ItaloTreno, arrive at Milano Rogoredo station.
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The distance between Rome and Segrate is 475 km. The road distance is 574 km.
ItaloTreno operates a train from Roma Termini to Milano Rogoredo hourly. Tickets cost €65–110 and the journey takes 2h 54m.