The average train between Rome and Paderborn takes 24h 16m and the fastest train takes 21h 4m. The train service runs several times per day from Rome to Paderborn. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Rome and Paderborn. The earliest departure is at 7:30 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Paderborn at 10:08 AM. All services require a transfer at Milano Centrale and take an average of 24h 16m. The schedules shown below are for the next available departures.
Arrives next day




25h 3m • 4 changes
Arrives next day




21h 4m • 4 changes
Arrives next day




25h 3m • 4 changes
Arrives next day




21h 4m • 4 changes
Arrives +2 days




38h 3m • 4 changes
Want to know about travelling from Rome to Paderborn? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Paderborn. However, there are services departing from Rome station and arriving at Paderborn station via Milano Centrale. The journey, including transfers, takes approximately 24h 16m.
Rome to Paderborn train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Paderborn train services, operated by ItaloTreno, arrive at Paderborn Hbf station.
Book your Rome to Paderborn train tickets online with ItaloTreno, Trenitalia EuroCity and 3 other operators.
The distance between Rome and Paderborn is 1,127.9 km. The road distance is 1,532 km.
You can take a train from Roma Termini to Paderborn Hbf via Milano Centrale, Arth-Goldau, Basel SBB, and Kassel-Wilhelmshoehe in around 15h 50m.