The average train between Rome and Melzo takes 3h 57m and the fastest train takes 3h 47m. There is a train service every few hours from Rome to Melzo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Rome and Melzo. The earliest departure is at 5:40 AM in the morning, and the last departure from Rome is at 8:05 PM which arrives into Melzo at 12:01 AM. All services require a transfer at Milano Centrale and take an average of 3h 57m. The schedules shown below are for the next available departures.

3h 54m • 1 change

3h 51m • 1 change

3h 54m • 1 change

3h 47m • 1 change

4h 19m • 1 change

3h 59m • 1 change

3h 54m • 1 change

3h 59m • 1 change

4h 19m • 1 change

3h 59m • 1 change

3h 54m • 1 change

3h 59m • 1 change

4h 19m • 1 change

3h 59m • 1 change

3h 54m • 1 change

3h 59m • 1 change
Want to know about travelling from Rome to Melzo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rome to Melzo. However, there are services departing from Rome station and arriving at Melzo station via Milano Centrale. The journey, including transfers, takes approximately 3h 57m.
Rome to Melzo train services, operated by ItaloTreno, depart from Roma Termini station.
Rome to Melzo train services, operated by ItaloTreno, arrive at Milano Centrale station.
Book your Rome to Melzo train tickets online with ItaloTreno and Trenord.
The distance between Rome and Melzo is 470.3 km. The road distance is 602 km.
ItaloTreno operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €75–150 and the journey takes 3h 5m.