The average train between Prestwick and Lockerbie takes 2h 27m and the fastest train takes 1h 41m. There is a train service every few hours from Prestwick to Lockerbie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Prestwick and Lockerbie. The earliest departure is at 5:20 AM in the morning, and the last departure from Prestwick is at 11:10 PM which arrives into Lockerbie at 5:52 AM. All services require a transfer, and take on average 2h 27m. The schedules shown below are for the next available departures.

2h 4m • 1 change

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1h 58m • 1 change

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2h 19m • 1 change

1h 58m • 1 change

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1h 58m • 1 change
Want to know about travelling from Prestwick to Lockerbie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prestwick to Lockerbie. However, there are services departing from Prestwick station and arriving at Lockerbie station via Glasgow Central. The journey, including transfers, takes approximately 2h 27m.
Prestwick to Lockerbie train services, operated by ScotRail, depart from Prestwick Town station.
Prestwick to Lockerbie train services, operated by ScotRail, arrive at Lockerbie station.
Book your Prestwick to Lockerbie train tickets online with ScotRail, TransPennine Express and Avanti West Coast.
The distance between Prestwick and Lockerbie is 89.6 km. The road distance is 182 km.
You can take a train from Prestwick Town to Lockerbie via Glasgow Central in around 2h 43m.