The average train between Prestwick and Derby takes 7h 20m and the fastest train takes 5h 29m. The train service runs several times per day from Prestwick to Derby. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prestwick and Derby. The earliest departure is at 6:40 AM in the morning, and the last departure from Prestwick is at 11:10 PM which arrives into Derby at 10:40 AM. All services require a transfer at Glasgow Central and take an average of 7h 20m. The schedules shown below are for the next available departures.


6h 11m • 2 changes
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Want to know about travelling from Prestwick to Derby? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prestwick to Derby. However, there are services departing from Prestwick station and arriving at Derby station via Glasgow Central. The journey, including transfers, takes approximately 7h 20m.
Prestwick to Derby train services, operated by ScotRail, depart from Prestwick Town station.
Prestwick to Derby train services, operated by ScotRail, arrive at Derby station.
Book your Prestwick to Derby train tickets online with ScotRail, Avanti West Coast and East Midlands Railways.
The distance between Prestwick and Derby is 351.4 km. The road distance is 530 km.
You can take a train from Prestwick Town to Derby via Glasgow Central and Crewe in around 7h.