The average train between Prestwich and London takes 2h 51m and the fastest train takes 2h 35m. The train runs at least 2 times per hour from Prestwich to London. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 30 minutes between Prestwich and London. The earliest departure is at 12:50 AM at night, and the last departure from Prestwich is at 11:50 PM which arrives into London at 7:27 AM. All services require a transfer at Piccadilly and take an average of 2h 51m. The schedules shown below are for the next available departures.

6h 36m • 1 change
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2h 48m • 1 change
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2h 48m • 1 changeWant to know about travelling from Prestwich to London? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prestwich to London. However, there are services departing from Manchester Piccadilly station and arriving at London Euston station via London Euston station. The journey, including transfers, takes approximately 2h 51m.
Prestwich to London train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Prestwich to London train services, operated by Avanti West Coast, arrive at London Euston station.
The distance between Prestwich and London is 268.3 km. The road distance is 305 km.
Avanti West Coast operates a train from Manchester Piccadilly to London Euston every 30 minutes. Tickets cost £60–100 and the journey takes 2h 8m.