The average train between Preston and Slough takes 3h 56m and the fastest train takes 3h 5m. There is a train service every few hours from Preston to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Preston and Slough. The earliest departure is at 3:15 AM at night, and the last departure from Preston is at 9:18 PM which arrives into Slough at 6:47 AM. All services require a transfer at London Euston and take an average of 3h 56m. The schedules shown below are for the next available departures.


4h 33m • 2 changes


4h 32m • 2 changes


3h 30m • 2 changes


3h 5m • 2 changes


4h 33m • 2 changes


4h 32m • 2 changes


3h 30m • 2 changes


3h 5m • 2 changes


5h 2m • 2 changes


4h 31m • 2 changes


3h 44m • 2 changes


3h 31m • 2 changes
Want to know about travelling from Preston to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Preston to Slough. However, there are services departing from Preston station and arriving at Slough station via London Euston. The journey, including transfers, takes approximately 3h 56m.
Preston to Slough train services, operated by Avanti West Coast, depart from Preston station.
Preston to Slough train services, operated by Avanti West Coast, arrive at Slough station.
Book your Preston to Slough train tickets online with Avanti West Coast, London Underground (Tube) and 2 other operators.
The distance between Preston and Slough is 288.1 km. The road distance is 369 km.
You can take a train from Preston to Slough via London Euston, Euston station, Tottenham Court Road station, and Tottenham Court Rd in around 3h 6m.