Train Preston to Slough from £103 | Tickets & Timetables

Trip Overview

The average train between Preston and Slough takes 3h 56m and the fastest train takes 3h 5m. There is a train service every few hours from Preston to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 56m
Duration: 229 mi
Distance: £103
Average price: Hourly
Frequency

Train

best

Take the train from Preston to London Eustontrain Glasgow Central - London Euston / ...
Take the train from Tottenham Court Rd to Sloughtrain Elizabeth

3h 8m

£66–152

Preston to Slough train times

Trains run hourly between Preston and Slough. The earliest departure is at 3:15 AM at night, and the last departure from Preston is at 9:18 PM which arrives into Slough at 6:47 AM. All services require a transfer at London Euston and take an average of 3h 56m. The schedules shown below are for the next available departures.

Departing Wednesday, May 20, 2026

3:15 AM → 7:48 AM
4h 33m • 2 changes
4:15 AM → 8:48 AM
4h 32m • 2 changes
5:33 AM → 9:03 AM
3h 30m • 2 changes
6:58 AM → 10:03 AM
3h 5m • 2 changes
Show more

Departing Thursday, May 21, 2026

3:15 AM → 7:48 AM
4h 33m • 2 changes
4:15 AM → 8:48 AM
4h 32m • 2 changes
5:33 AM → 9:03 AM
3h 30m • 2 changes
6:58 AM → 10:03 AM
3h 5m • 2 changes
Show more

Departing Friday, May 22, 2026

3:15 AM → 7:48 AM
4h 33m • 2 changes
4:15 AM → 8:48 AM
4h 32m • 2 changes
5:33 AM → 9:03 AM
3h 30m • 2 changes
6:58 AM → 10:03 AM
3h 5m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Preston to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.