The average train between Preston and Science Museum takes 3h 12m and the fastest train takes 2h 32m. There is a train service every few hours from Preston to Science Museum. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Preston and Science Museum. The earliest departure is at 3:15 AM at night, and the last departure from Preston is at 9:18 PM which arrives into Science Museum at 5:54 AM. All services require a transfer at London Euston and take an average of 3h 12m. The schedules shown below are for the next available departures.

3h 50m • 1 change

2h 46m • 1 change

2h 34m • 1 change

2h 57m • 1 change

4h 3m • 1 change

3h 50m • 1 change

2h 46m • 1 change

2h 34m • 1 change

4h 3m • 1 change

3h 50m • 1 change

2h 46m • 1 change

2h 34m • 1 change
Want to know about travelling from Preston to Science Museum? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Preston to Science Museum. However, there are services departing from Preston station and arriving at Science Museum station via London Euston. The journey, including transfers, takes approximately 3h 12m.
Preston to Science Museum train services, operated by Caledonian Sleeper, depart from Preston station.
Preston to Science Museum train services, operated by Caledonian Sleeper, arrive at London Euston station.
The distance between Preston and Science Museum is 304.3 km. The road distance is 341 km.
Avanti West Coast operates a train from Preston to London Euston hourly. Tickets cost £75–130 and the journey takes 2h 15m. Caledonian Sleeper also services this route twice daily.