The average train between Prague and Siena takes 20h 58m and the fastest train takes 16h 5m. The train service runs several times per day from Prague to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Prague and Siena. The earliest departure is at 4:35 AM at night, and the last departure from Prague is at 6:37 PM which arrives into Siena at 8:40 PM. All services require a transfer at Wien Hbf and take an average of 20h 58m. The schedules shown below are for the next available departures.
Want to know about travelling from Prague to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Siena. However, there are services departing from Prague station and arriving at Siena station via Wien Hbf. The journey, including transfers, takes approximately 20h 58m.
Prague to Siena train services, operated by České dráhy (ČD), depart from Praha Hlavni Nadrazi station.
Prague to Siena train services, operated by České dráhy (ČD), arrive at Siena station.
Book your Prague to Siena train tickets online with České dráhy (ČD), Railjet and 2 other operators.
The distance between Prague and Siena is 788.6 km. The road distance is 1,415 km.
You can take a train from Praha Hlavni Nadrazi to Siena via Wien Hbf, Venezia Mestre, and Firenze S.M.N. in around 16h 29m.
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