The train between Prague and Potsdam takes 4h 41m. The train service runs several times per day from Prague to Potsdam. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Prague and Potsdam. The earliest departure is at 6:31 AM in the morning, and the last departure from Prague is at 4:31 PM which arrives into Potsdam at 9:12 PM. All services require a transfer, and take on average 4h 41m. The schedules shown below are for the next available departures.

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Want to know about travelling from Prague to Potsdam? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Potsdam. However, there are services departing from Prague station and arriving at Potsdam station via Berlin Hbf. The journey, including transfers, takes approximately 4h 41m.
Prague to Potsdam train services, operated by České dráhy (ČD), depart from Praha Hlavni Nadrazi station.
Prague to Potsdam train services, operated by České dráhy (ČD), arrive at Berlin Hbf station.
The distance between Prague and Potsdam is 273.7 km. The road distance is 398 km.
České dráhy (ČD) operates a train from Praha Hlavni Nadrazi to Berlin Hbf every 4 hours. Tickets cost €40–75 and the journey takes 3h 58m. Deutsche Bahn also services this route every 4 hours.