The average train between Prague and Merseburg takes 5h 27m and the fastest train takes 4h 48m. The train service runs several times per day from Prague to Merseburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Merseburg. The earliest departure is at 12:42 AM at night, and the last departure from Prague is at 8:57 PM which arrives into Merseburg at 7:31 AM. All services require a transfer at Dresden Hauptbahnhof and take an average of 5h 27m. The schedules shown below are for the next available departures.



6h 49m • 3 changes



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Arrives next day



10h 34m • 3 changes



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4h 50m • 3 changes



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4h 48m • 3 changes



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4h 48m • 3 changes
Want to know about travelling from Prague to Merseburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Merseburg. However, there are services departing from Prague station and arriving at Merseburg station via Dresden Hbf. The journey, including transfers, takes approximately 5h 27m.
Prague to Merseburg train services, operated by Railjet, depart from Praha-Holesovice station.
Prague to Merseburg train services, operated by Railjet, arrive at Leipzig Hbf station.
Book your Prague to Merseburg train tickets online with Railjet, Deutsche Bahn Intercity (DB IC) and 5 other operators.
The distance between Prague and Merseburg is 221.7 km. The road distance is 350 km.
You can take a train from Praha-Holesovice to Merseburg Hbf via Dresden Hauptbahnhof, Leipzig Hbf, and Halle(Saale)Hbf in around 4h 38m.