The average train between Prague and Dessau takes 6h 16m and the fastest train takes 5h 18m. The train service runs several times per day from Prague to Dessau. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Dessau. The earliest departure is at 12:42 AM at night, and the last departure from Prague is at 6:41 PM which arrives into Dessau at 5:59 AM. All services require a transfer at Dresden Hauptbahnhof and take an average of 6h 16m. The schedules shown below are for the next available departures.


6h 17m • 2 changes


5h 18m • 2 changes
Arrives next day


11h 18m • 2 changes


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6h 17m • 2 changes


5h 18m • 2 changes


5h 18m • 2 changes


5h 18m • 2 changes


6h 17m • 2 changes


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5h 18m • 2 changes


5h 18m • 2 changes


6h 17m • 2 changes


5h 18m • 2 changes


5h 18m • 2 changes


5h 18m • 2 changes


6h 17m • 2 changes


5h 18m • 2 changes


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5h 18m • 2 changes
Want to know about travelling from Prague to Dessau? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Dessau. However, there are services departing from Prague station and arriving at Dessau station via Dresden Hbf. The journey, including transfers, takes approximately 6h 16m.
Prague to Dessau train services, operated by ÖBB EuroCity, depart from Praha-Holesovice station.
Prague to Dessau train services, operated by ÖBB EuroCity, arrive at Dessau Hbf station.
Book your Prague to Dessau train tickets online with ÖBB EuroCity, Deutsche Bahn Regio (DB Regional) and 3 other operators.
The distance between Prague and Dessau is 247.2 km. The road distance is 363 km.
You can take a train from Praha-Holesovice to Dessau Hbf via Dresden Hauptbahnhof and Leipzig Hbf in around 4h 50m.