The average train between Prague and Berlin (State) takes 4h 7m and the fastest train takes 3h 56m. The train service runs several times per day from Prague to Berlin (State). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Berlin (State). The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 5:38 PM which arrives into Berlin (State) at 11:02 PM. All services require a transfer, and take on average 4h 7m. The schedules shown below are for the next available departures.

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3h 58m • 1 change

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3h 56m • 1 change

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3h 56m • 1 change

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3h 58m • 1 change

3h 56m • 1 change
Want to know about travelling from Prague to Berlin (State)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Berlin (State). However, there are services departing from Prague station and arriving at Berlin (State) station via Berlin Hbf. The journey, including transfers, takes approximately 4h 7m.
Prague to Berlin (State) train services, operated by Railjet, depart from Praha-Holesovice station.
Prague to Berlin (State) train services, operated by Railjet, arrive at Berlin Hbf station.
The distance between Prague and Berlin (State) is 277.1 km. The road distance is 370 km.
České dráhy (ČD) operates a train from Praha-Holesovice to Berlin Hbf every 4 hours. Tickets cost €40–65 and the journey takes 3h 48m. Two other operators also service this route.