The average train between Pisa and Sezze takes 4h 21m and the fastest train takes 3h 28m. There is a train service every few hours from Pisa to Sezze. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Pisa and Sezze. The earliest departure is at 4:15 AM at night, and the last departure from Pisa is at 8:56 PM which arrives into Sezze at 6:13 AM. All services require a transfer at Firenze S.M.N. and take an average of 4h 21m. The schedules shown below are for the next available departures.


5h 45m • 2 changes


5h 9m • 2 changes


3h 52m • 2 changes


3h 52m • 2 changes


4h 42m • 2 changes


4h 46m • 2 changes


3h 46m • 2 changes


3h 28m • 2 changes


5h 10m • 2 changes


4h 46m • 2 changes


3h 46m • 2 changes


3h 52m • 2 changes


4h 42m • 2 changes


4h 46m • 2 changes


3h 46m • 2 changes


3h 28m • 2 changes
Want to know about travelling from Pisa to Sezze? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Sezze. However, there are services departing from Pisa station and arriving at Sezze station via Firenze S.M.N.. The journey, including transfers, takes approximately 4h 21m.
Pisa to Sezze train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Sezze train services, operated by Trenitalia, arrive at Sezze Romano station.
Book your Pisa to Sezze train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Pisa and Sezze is 328 km. The road distance is 409 km.
You can take a train from Pisa Centrale to Sezze Romano via Firenze S.M.N. and Roma Termini in around 4h 42m.