The average train between Pisa and Brussels takes 18h 9m and the fastest train takes 12h 45m. The train service runs several times per day from Pisa to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Pisa and Brussels. The earliest departure is at 8:32 AM in the morning, and the last departure from Pisa is at 7:09 PM which arrives into Brussels at 3:17 PM. All services require a transfer at Firenze S.M.N. and take an average of 18h 9m. The schedules shown below are for the next available departures.
Arrives next day




20h 13m • 4 changes
Arrives next day




20h 8m • 4 changes




13h 45m • 4 changes
Arrives next day




22h 15m • 4 changes
Arrives next day




20h 8m • 4 changes
Want to know about travelling from Pisa to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Brussels. However, there are services departing from Pisa station and arriving at Brussels station via Firenze S.M.N.. The journey, including transfers, takes approximately 18h 9m.
Pisa to Brussels train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Brussels train services, operated by Trenitalia, arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Pisa to Brussels train tickets online with Trenitalia, Trenitalia Frecce and 3 other operators.
The distance between Pisa and Brussels is 915.4 km. The road distance is 1,551 km.
You can take a train from Pisa Centrale to Brussel-Zuid / Bruxelles-Midi via Firenze S.M.N., Torino Porta Susa, Paris Gare de Lyon, and Paris Nord in around 13h 44m.