The average train between Pescara and Isernia takes 8h 11m and the fastest train takes 5h 53m. The train service runs several times per day from Pescara to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Pescara and Isernia. The earliest departure is at 12:47 PM in the afternoon, and the last departure from Pescara is at 8:57 PM which arrives into Isernia at 9:21 AM. All services require a transfer at Foggia and take an average of 8h 11m. The schedules shown below are for the next available departures.


6h 33m • 2 changes


5h 53m • 2 changes
Arrives next day


12h 24m • 2 changes


6h 33m • 2 changes


5h 53m • 2 changes
Arrives next day


12h 24m • 2 changes


6h 33m • 2 changes


5h 53m • 2 changes
Arrives next day


12h 24m • 2 changes


6h 33m • 2 changes


5h 53m • 2 changes
Arrives next day


12h 24m • 2 changes
Want to know about travelling from Pescara to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pescara to Isernia. However, there are services departing from Pescara station and arriving at Isernia station via Foggia. The journey, including transfers, takes approximately 8h 11m.
Pescara to Isernia train services, operated by Trenitalia Frecce, depart from Pescara Centrale station.
Pescara to Isernia train services, operated by Trenitalia Frecce, arrive at Isernia station.
Book your Pescara to Isernia train tickets online with Trenitalia Frecce, Trenitalia and Trenitalia Intercity.
The distance between Pescara and Isernia is 95.9 km. The road distance is 422 km.
You can take a train from Pescara Centrale to Isernia via Foggia and Caserta in around 6h 28m.