Rome2Rio

Palermo to Manchester trains

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Trip Overview

The average train between Palermo and Manchester takes 45h 32m and the fastest train takes 38h 14m. The train runs, on average, 2 times per week from Palermo to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

45h 32m
Duration
1,914 mi
Distance
£676
Average price
Twice a week
Frequency

Palermo to Manchester train times

Trains run twice a week between Palermo and Manchester. The service departs Palermo at 7:05 AM in the morning, which arrives into Manchester at 10:55:00. All services require a transfer at Roma Termini and take an average of 45h 32m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Trenitalia IntercityItaloTrenoTrenitaliaEurostarEurostarAvanti West Coast2d 4h • 5 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitaliaEurostarEurostarAvanti West Coast38h 14m • 5 changes

Frequently asked questions

Want to know about travelling from Palermo to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Palermo to Manchester.ExpandLaunch map view
  • Distance: 1,913.8 mi
  • Duration: 45h 32m

What companies run services between Palermo, Italy and Manchester, England?

You can take a train from Palermo Centrale to Manchester Piccadilly via Roma Termini, Milano Centrale, Chambery Challes Les Eaux, Lille Europe, London St Pancras Intl, and London Euston in around 28h 47m.

Operators