The average train between Palermo and Isernia takes 11h 49m and the fastest train takes 11h 3m. The train service runs several times per day from Palermo to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Palermo and Isernia. The earliest departure is at 7:05 AM in the morning, and the last departure from Palermo is at 10:15 AM which arrives into Isernia at 9:43 PM. All services require a transfer, and take on average 11h 49m. The schedules shown below are for the next available departures.
Want to know about travelling from Palermo to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Palermo to Isernia. However, there are services departing from Palermo station and arriving at Isernia station via Napoli Centrale. The journey, including transfers, takes approximately 11h 49m.
Palermo to Isernia train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
Palermo to Isernia train services, operated by Trenitalia Intercity, arrive at Isernia station.
Book your Palermo to Isernia train tickets online with Trenitalia Intercity and Trenitalia.
The distance between Palermo and Isernia is 392.7 km. The road distance is 782 km.
You can take a train from Palermo Centrale to Isernia via Napoli Centrale in around 12h 11m.
