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The train between Palermo and Isernia takes 12h 15m. The train runs, on average, once a week from Palermo to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once a week between Palermo and Isernia. The service departs Palermo at 7:05 AM in the morning, which arrives into Isernia at 19:20:00. All services require a transfer, and take on average 12h 15m. The schedules shown below are for the next available departures.
Want to know about travelling from Palermo to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Palermo to Isernia. However, there are services departing from Palermo Centrale station and arriving at Isernia station via Caserta station. The journey, including transfers, takes approximately 12h 15m.
Palermo to Isernia train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
Palermo to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Palermo to Isernia train tickets online with Omio.
The distance between Palermo and Isernia is 392.7 km.
You can take a train from Palermo Centrale to Isernia via Caserta in around 11h 29m.
