The average train between Paderborn and Mannheim takes 4h and the fastest train takes 3h 40m. There is a train service every few hours from Paderborn to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Paderborn and Mannheim. The earliest departure is at 5:43 AM in the morning, and the last departure from Paderborn is at 9:48 PM which arrives into Mannheim at 6:29 AM. All services require a transfer, and take on average 4h. The schedules shown below are for the next available departures.

4h 9m • 1 change

3h 41m • 1 change

3h 42m • 1 change

3h 41m • 1 change

3h 46m • 1 change

3h 42m • 1 change

3h 41m • 1 change

3h 42m • 1 change

3h 42m • 1 change

3h 41m • 1 change

3h 42m • 1 change

3h 41m • 1 change

3h 41m • 1 change

3h 42m • 1 change

3h 41m • 1 change

4h 9m • 1 change
Want to know about travelling from Paderborn to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Paderborn to Mannheim. However, there are services departing from Paderborn station and arriving at Mannheim station via Kassel-Wilhelmshoehe. The journey, including transfers, takes approximately 4h.
Paderborn to Mannheim train services, operated by National Express, depart from Paderborn Hbf station.
Paderborn to Mannheim train services, operated by National Express, arrive at Mannheim, Hauptbahnhof station.
Book your Paderborn to Mannheim train tickets online with National Express and Deutsche Bahn Intercity (DB IC).
The distance between Paderborn and Mannheim is 248.8 km. The road distance is 374 km.
You can take a train from Paderborn Hbf to Mannheim, Hauptbahnhof via Kassel Bahnhof Wilhelmshöhe in around 3h 45m.