The average train between Otranto and Perugia takes 18h 49m and the fastest train takes 10h 47m. The train service runs several times per day from Otranto to Perugia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Otranto and Perugia. The earliest departure is at 10:50 AM in the morning, and the last departure from Otranto is at 8:13 PM which arrives into Perugia at 4:58 PM. All services require a transfer at Maglie and take an average of 18h 49m. The schedules shown below are for the next available departures.




10h 47m • 4 changes
Arrives next day




22h 18m • 4 changes
Arrives +2 days




44h 45m • 4 changes




10h 47m • 4 changes
Arrives next day




21h 38m • 4 changes
Arrives next day




20h 45m • 4 changes




10h 47m • 4 changes
Arrives next day




21h 38m • 4 changes
Arrives next day




20h 45m • 4 changes




10h 47m • 4 changes
Arrives next day




21h 38m • 4 changes
Arrives next day




20h 45m • 4 changes
Want to know about travelling from Otranto to Perugia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Otranto to Perugia. However, there are services departing from Otranto station and arriving at Perugia station via Ancona. The journey, including transfers, takes approximately 18h 49m.
Otranto to Perugia train services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., depart from Lecce station.
Otranto to Perugia train services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., arrive at Foligno station.
Book your Otranto to Perugia train tickets online with Ferrovie del Sud Est e Servizi Automobilistici S.r.l., Trenitalia Frecce and Trenitalia.
The distance between Otranto and Perugia is 604.3 km. The road distance is 806 km.
You can take a train from Otranto to Perugia via Maglie, Lecce, Ancona, and Foligno in around 12h 42m.