The average train between Opera and Rome takes 4h 55m and the fastest train takes 3h 55m. The train service runs several times per day from Opera to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Opera and Rome. The earliest departure is at 6:00 AM in the morning, and the last departure from Opera is at 10:00 PM which arrives into Rome at 9:19 AM. All services require a transfer at Milan Rogoredo and take an average of 4h 55m. The schedules shown below are for the next available departures.


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Arrives next day


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5h 24m • 2 changes


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5h 24m • 2 changes
Want to know about travelling from Opera to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Opera to Rome. However, there are services departing from Opera station and arriving at Rome station via Roma Termini. The journey, including transfers, takes approximately 4h 55m.
Opera to Rome train services, operated by Trenord, depart from Milano Centrale station.
Opera to Rome train services, operated by Trenord, arrive at Roma Termini station.
The distance between Opera and Rome is 468 km. The road distance is 599 km.
ItaloTreno operates a train from Milano Centrale to Roma Termini every 30 minutes. Tickets cost €75–160 and the journey takes 3h 5m.