The average train between Novi Ligure and Rome takes 5h 51m and the fastest train takes 4h 50m. The train service runs several times per day from Novi Ligure to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Novi Ligure and Rome. The earliest departure is at 6:36 AM in the morning, and the last departure from Novi Ligure is at 8:40 PM which arrives into Rome at 9:04 AM. All services require a transfer, and take on average 5h 51m. The schedules shown below are for the next available departures.

4h 55m • 1 change

5h 9m • 1 change

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5h 9m • 1 change

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5h 9m • 1 change

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5h 9m • 1 change
Want to know about travelling from Novi Ligure to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Novi Ligure to Rome. However, there are services departing from Novi Ligure station and arriving at Rome station via Milan Rogoredo. The journey, including transfers, takes approximately 5h 51m.
Novi Ligure to Rome train services, operated by Trenord, depart from Novi Ligure station.
Novi Ligure to Rome train services, operated by Trenord, arrive at Roma Termini station.
Book your Novi Ligure to Rome train tickets online with Trenord and Trenitalia Frecce.
The distance between Novi Ligure and Rome is 437.5 km. The road distance is 646 km.
You can take a train from Novi Ligure to Roma Termini via Milano Rogoredo in around 5h 12m.