The average train between Neuss and Mannheim takes 2h 20m and the fastest train takes 2h 8m. There is an hourly train service from Neuss to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Neuss and Mannheim. The earliest departure is at 5:35 AM in the morning, and the last departure from Neuss is at 9:05 PM which arrives into Mannheim at 11:25 PM. All services require a transfer at Duesseldorf Hbf and take an average of 2h 20m. The schedules shown below are for the next available departures.

2h 8m • 1 change

2h 18m • 1 change

2h 19m • 1 change

2h 37m • 1 change

2h 51m • 1 change

2h 18m • 1 change

2h 29m • 1 change

2h 37m • 1 change

2h 29m • 1 change

2h 20m • 1 change

2h 21m • 1 change

2h 37m • 1 change
Want to know about travelling from Neuss to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Neuss to Mannheim. However, there are services departing from Neuss station and arriving at Mannheim station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 2h 20m.
Neuss to Mannheim train services, operated by Deutsche Bahn Regio (DB Regional), depart from Düsseldorf Hbf station.
Neuss to Mannheim train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Book your Neuss to Mannheim train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Neuss and Mannheim is 228.2 km. The road distance is 290 km.
Deutsche Bahn Intercity (DB IC) operates a train from Düsseldorf Hbf to Mannheim, Hauptbahnhof hourly. Tickets cost €50–130 and the journey takes 1h 59m. Nederlandse Spoorwegen (NS) also services this route 3 times a day.