The average train between Natick and Poughkeepsie takes 8h 17m and the fastest train takes 6h 36m. The train service runs several times per day from Natick to Poughkeepsie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Natick and Poughkeepsie. The earliest departure is at 12:14 AM at night, and the last departure from Natick is at 11:39 PM which arrives into Poughkeepsie at 11:43 AM. All services require a transfer at Back Bay and take an average of 8h 17m. The schedules shown below are for the next available departures.


6h 56m • 2 changes


7h 13m • 2 changes


7h 17m • 2 changes


6h 36m • 2 changes


6h 56m • 2 changes


7h 13m • 2 changes


7h 17m • 2 changes


6h 36m • 2 changes


6h 45m • 2 changes


6h 49m • 2 changes


6h 42m • 2 changes


7h 12m • 2 changes


6h 46m • 2 changes


6h 46m • 2 changes


8h 7m • 2 changes


7h 21m • 2 changes


12h 20m • 2 changes


6h 46m • 2 changes


8h 7m • 2 changes


7h 21m • 2 changes


11h 29m • 2 changes


6h 56m • 2 changes


7h 13m • 2 changes


7h 17m • 2 changes
Want to know about travelling from Natick to Poughkeepsie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Natick to Poughkeepsie. However, there are services departing from Natick station and arriving at Poughkeepsie station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 8h 17m.
Natick to Poughkeepsie train services, operated by MBTA, depart from Boston station.
Natick to Poughkeepsie train services, operated by MBTA, arrive at Poughkeepsie Amtrak Station.
The distance between Natick and Poughkeepsie is 222.2 km. The road distance is 514 km.
You can take a train from Natick Center to Poughkeepsie Amtrak Station via Back Bay, Boston, and Ny Moynihan Train Hall At Penn Station in around 7h 39m.