The average train between Natick and Philadelphia takes 6h 52m and the fastest train takes 5h 47m. There is a train service every few hours from Natick to Philadelphia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Natick and Philadelphia. The earliest departure is at 5:05 AM in the morning, and the last departure from Natick is at 11:40 PM which arrives into Philadelphia at 10:08 AM. All services require a transfer at Back Bay and take an average of 6h 52m. The schedules shown below are for the next available departures.

6h 3m • 1 change

6h 20m • 1 change

5h 47m • 1 change

6h 11m • 1 change

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6h 20m • 1 change

5h 47m • 1 change

6h 11m • 1 change

6h 3m • 1 change

6h 20m • 1 change

5h 47m • 1 change

6h 11m • 1 change

6h 3m • 1 change

6h 20m • 1 change

5h 47m • 1 change

6h 11m • 1 change
Want to know about travelling from Natick to Philadelphia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Natick to Philadelphia. However, there are services departing from Natick station and arriving at Philadelphia station via 30th Street Station station. The journey, including transfers, takes approximately 6h 52m.
Natick to Philadelphia train services, operated by MBTA, depart from Boston station.
Natick to Philadelphia train services, operated by MBTA, arrive at 30th Street Station.
The distance between Natick and Philadelphia is 411.3 km. The road distance is 542 km.
Amtrak Acela operates a train from Boston to 30th Street Station every 4 hours. Tickets cost $70–800 and the journey takes 4h 57m. Amtrak Northeast Regional also services this route every 3 hours.