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Natick to Chicago trains

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Trip Overview

The average train between Natick and Chicago takes 22h 50m and the fastest train takes 22h 43m. The train runs, on average, 6 times per week from Natick to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 50m
Duration
997 mi
Distance
$655
Average price
6 times a week
Frequency

Natick to Chicago train times

Trains run 6 times a week between Natick and Chicago. The earliest departure is at 11:44 AM in the morning, and the last departure from Natick is at 12:29 PM which arrives into Chicago at 10:12 AM. All services require a transfer, and take on average 22h 50m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

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    Arrives next day

    MBTAAmtrak22h 43m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    MBTAAmtrak22h 43m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    MBTAAmtrak22h 43m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    MBTAAmtrak22h 43m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    MBTAAmtrak22h 43m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    MBTAAmtrak23h 28m • 1 change

Frequently asked questions

Want to know about travelling from Natick to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Natick to Chicago.ExpandLaunch map view
  • Distance: 996.9 mi
  • Duration: 22h 50m

What companies run services between Natick, MA, USA and Chicago, IL, USA?

Amtrak operates a train from Framingham Amtrak to Chicago Union Station once daily. Tickets cost $500–850 and the journey takes 21h 47m.

Operators