The average train between Natick and Baltimore takes 8h 18m and the fastest train takes 6h 54m. The train service runs several times per day from Natick to Baltimore. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Natick and Baltimore. The earliest departure is at 5:05 AM in the morning, and the last departure from Natick is at 11:40 PM which arrives into Baltimore at 12:18 PM. All services require a transfer at Back Bay and take an average of 8h 18m. The schedules shown below are for the next available departures.

7h 7m • 1 change

7h 27m • 1 change

6h 54m • 1 change

7h 16m • 1 change

7h 7m • 1 change

7h 27m • 1 change

6h 54m • 1 change

7h 16m • 1 change

7h 7m • 1 change

7h 27m • 1 change

6h 54m • 1 change

7h 16m • 1 change

7h 7m • 1 change

7h 27m • 1 change

6h 54m • 1 change

7h 16m • 1 change

8h 14m • 1 change

7h 54m • 1 change

7h 12m • 1 change

7h 18m • 1 change
Want to know about travelling from Natick to Baltimore? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Natick to Baltimore. However, there are services departing from Natick station and arriving at Baltimore station via Baltimore Penn Station station. The journey, including transfers, takes approximately 8h 18m.
Natick to Baltimore train services, operated by MBTA, depart from Boston station.
Natick to Baltimore train services, operated by MBTA, arrive at Baltimore Penn Station.
The distance between Natick and Baltimore is 554 km. The road distance is 693 km.
Amtrak Acela operates a train from Boston to Baltimore Penn Station every 4 hours. Tickets cost $95–900 and the journey takes 6h 10m. Amtrak Northeast Regional also services this route every 4 hours.