The average train between Naples and Brindisi takes 5h 25m and the fastest train takes 5h. The train service runs several times per day from Naples to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Naples and Brindisi. The earliest departure is at 8:06 AM in the morning, and the last departure from Naples is at 6:12 PM which arrives into Brindisi at 11:20 PM. All services require a transfer, and take on average 5h 25m. The schedules shown below are for the next available departures.

5h 46m • 1 change

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5h • 1 change

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5h 27m • 1 change

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6h 3m • 1 change

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5h 30m • 1 change

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6h 46m • 1 change

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5h 19m • 1 change
Want to know about travelling from Naples to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Naples to Brindisi. However, there are services departing from Naples station and arriving at Brindisi station via Brindisi. The journey, including transfers, takes approximately 5h 25m.
Naples to Brindisi train services, operated by Trenitalia, depart from Caserta station.
Naples to Brindisi train services, operated by Trenitalia, arrive at Brindisi station.
Book your Naples to Brindisi train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Naples and Brindisi is 310 km. The road distance is 424 km.
Trenitalia Frecce operates a train from Caserta to Brindisi 5 times a day. Tickets cost €55–110 and the journey takes 4h 14m.