The average train between Most and Brno takes 5h 9m and the fastest train takes 4h 47m. The train service runs several times per day from Most to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Most and Brno. The earliest departure is at 5:26 AM in the morning, and the last departure from Most is at 8:26 PM which arrives into Brno at 3:49 AM. All services require a transfer, and take on average 5h 9m. The schedules shown below are for the next available departures.

4h 47m • 1 change

4h 47m • 1 change

4h 47m • 1 change

4h 51m • 1 change

4h 47m • 1 change

4h 47m • 1 change

5h 14m • 1 change

4h 47m • 1 change

4h 47m • 1 change

4h 47m • 1 change

5h 14m • 1 change

4h 47m • 1 change

4h 47m • 1 change

5h 14m • 1 change

4h 47m • 1 change

4h 47m • 1 change

4h 47m • 1 change

5h 14m • 1 change

4h 47m • 1 change

4h 47m • 1 change

4h 47m • 1 change

5h 14m • 1 change

4h 47m • 1 change

4h 47m • 1 change
Want to know about travelling from Most to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Most to Brno. However, there are services departing from Most station and arriving at Brno station via Praha Hlavni Nadrazi. The journey, including transfers, takes approximately 5h 9m.
Most to Brno train services, operated by České dráhy (ČD), depart from Most station.
Most to Brno train services, operated by České dráhy (ČD), arrive at Brno Hlavni Nadrazi station.
The distance between Most and Brno is 257.9 km. The road distance is 404 km.
You can take a train from Most to Brno Hlavni Nadrazi via Praha Hlavni Nadrazi in around 4h 52m.