The average train between Mosbach and Brussels takes 6h 18m and the fastest train takes 5h 21m. The train service runs several times per day from Mosbach to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mosbach and Brussels. The earliest departure is at 4:54 AM at night, and the last departure from Mosbach is at 11:07 PM which arrives into Brussels at 9:26 AM. All services require a transfer at Heidelberg, Hauptbahnhof and take an average of 6h 18m. The schedules shown below are for the next available departures.


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5h 21m • 2 changes
Want to know about travelling from Mosbach to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mosbach to Brussels. However, there are services departing from Mosbach station and arriving at Brussels station via Heidelberg, Hauptbahnhof. The journey, including transfers, takes approximately 6h 18m.
Mosbach to Brussels train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mosbach, Bahnhof station.
Mosbach to Brussels train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Brussels-Nord station.
Book your Mosbach to Brussels train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Mosbach and Brussels is 380.7 km. The road distance is 537 km.
You can take a train from Mosbach, Bahnhof to Brussels-Nord via Heidelberg, Hauptbahnhof and Frankfurt in around 6h 8m.