The average train between Milan and Popoli takes 7h 53m and the fastest train takes 5h 36m. The train service runs several times per day from Milan to Popoli. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Milan and Popoli. The earliest departure is at 5:25 AM in the morning, and the last departure from Milan is at 5:50 PM which arrives into Popoli at 7:57 AM. All services require a transfer, and take on average 7h 53m. The schedules shown below are for the next available departures.

5h 51m • 1 change
5h 44m • 1 change
5h 47m • 1 changeArrives next day

15h 49m • 1 change
7h 42m • 1 change
5h 36m • 1 change
5h 46m • 1 changeArrives next day

14h 7m • 1 change
6h 28m • 1 change
5h 44m • 1 change
5h 47m • 1 changeArrives next day

14h 7m • 1 change
6h 28m • 1 change
5h 44m • 1 change
5h 47m • 1 changeArrives next day

14h 7m • 1 change
6h 28m • 1 change
5h 44m • 1 change
5h 47m • 1 changeArrives next day

14h 7m • 1 changeWant to know about travelling from Milan to Popoli? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Popoli. However, there are services departing from Milan station and arriving at Popoli station via Pescara Centrale. The journey, including transfers, takes approximately 7h 53m.
Milan to Popoli train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Popoli train services, operated by Trenitalia Frecce, arrive at Popoli-Vittorito station.
Book your Milan to Popoli train tickets online with Trenitalia Frecce, Trenitalia and Trenitalia Intercity.
The distance between Milan and Popoli is 522.2 km. The road distance is 616 km.
You can take a train from Milano Centrale to Popoli-Vittorito via Pescara Centrale in around 5h 59m.