The average train between Milan and Popoli takes 7h 12m and the fastest train takes 5h 58m. The train service runs several times per day from Milan to Popoli. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Milan and Popoli. The earliest departure is at 10:10 AM in the morning, and the last departure from Milan is at 5:10 PM which arrives into Popoli at 7:57 AM. All services require a transfer at Reggio Emilia Av and take an average of 7h 12m. The schedules shown below are for the next available departures.


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Want to know about travelling from Milan to Popoli? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Popoli. However, there are services departing from Milan station and arriving at Popoli station via Reggio Emilia Av. The journey, including transfers, takes approximately 7h 12m.
Milan to Popoli train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Popoli train services, operated by Trenitalia Frecce, arrive at Popoli-Vittorito station.
Book your Milan to Popoli train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Milan and Popoli is 522.2 km. The road distance is 616 km.
You can take a train from Milano Centrale to Popoli-Vittorito via Reggio Emilia Av and Pescara Centrale in around 6h 58m.