The average train between Milan and Nyon takes 5h 5m and the fastest train takes 4h 37m. The train service runs several times per day from Milan to Nyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Milan and Nyon. The earliest departure is at 7:10 AM in the morning, and the last departure from Milan is at 7:10 PM which arrives into Nyon at 11:47 PM. All services require a transfer at Domodossola and take an average of 5h 5m. The schedules shown below are for the next available departures.


5h 9m • 2 changes


5h 14m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 14m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 11m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 11m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 11m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 11m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 9m • 2 changes


5h 11m • 2 changes
Want to know about travelling from Milan to Nyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Nyon. However, there are services departing from Milan station and arriving at Nyon station via Domodossola. The journey, including transfers, takes approximately 5h 5m.
Milan to Nyon train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
Milan to Nyon train services, operated by Trenitalia EuroCity, arrive at Nyon station.
Book your Milan to Nyon train tickets online with Trenitalia EuroCity, BLS AG and Swiss Federal Railways (SBB CFF FFS).
The distance between Milan and Nyon is 250 km. The road distance is 342 km.
You can take a train from Milano Centrale to Nyon via Domodossola and Brig in around 5h 27m.