The average train between Milan and Mannheim takes 7h 11m and the fastest train takes 6h 48m. The train service runs several times per day from Milan to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Milan and Mannheim. The earliest departure is at 7:10 AM in the morning, and the last departure from Milan is at 6:05 PM which arrives into Mannheim at 1:53 AM. All services require a transfer, and take on average 7h 11m. The schedules shown below are for the next available departures.

7h 12m • 1 change
7h 12m • 1 change
6h 48m • 1 change
7h 12m • 1 change
7h 12m • 1 change
7h 12m • 1 change
6h 48m • 1 change
7h 12m • 1 change
7h 12m • 1 change
7h 12m • 1 change
6h 55m • 1 change
7h 12m • 1 changeWant to know about travelling from Milan to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Mannheim. However, there are services departing from Milan station and arriving at Mannheim station via Basel Sbb. The journey, including transfers, takes approximately 7h 11m.
Milan to Mannheim train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
Milan to Mannheim train services, operated by Trenitalia EuroCity, arrive at Mannheim, Hauptbahnhof station.
Book your Milan to Mannheim train tickets online with Trenitalia EuroCity and Deutsche Bahn Intercity (DB IC).
The distance between Milan and Mannheim is 450.8 km. The road distance is 616 km.
You can take a train from Milano Centrale to Mannheim, Hauptbahnhof via Basel SBB in around 6h 53m.