The average train between Milan and Kassel takes 12h 16m and the fastest train takes 10h 1m. The train service runs several times per day from Milan to Kassel. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Milan and Kassel. The earliest departure is at 7:10 AM in the morning, and the last departure from Milan is at 6:05 PM which arrives into Kassel at 9:11 AM. All services require a transfer, and take on average 12h 16m. The schedules shown below are for the next available departures.

10h 1m • 1 change
10h 1m • 1 changeArrives next day

15h 6m • 1 change
10h 1m • 1 change
10h 1m • 1 changeArrives next day

15h 6m • 1 changeWant to know about travelling from Milan to Kassel? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Kassel. However, there are services departing from Milan station and arriving at Kassel station via Basel Sbb. The journey, including transfers, takes approximately 12h 16m.
Milan to Kassel train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
Milan to Kassel train services, operated by Trenitalia EuroCity, arrive at Kassel Bahnhof Wilhelmshöhe station.
Book your Milan to Kassel train tickets online with Trenitalia EuroCity and Deutsche Bahn Intercity (DB IC).
The distance between Milan and Kassel is 651.2 km. The road distance is 885 km.
You can take a train from Milano Centrale to Kassel Bahnhof Wilhelmshöhe via Basel SBB in around 9h 45m.