Middlesex to Manchester Trains

Middlesex to Manchester trains

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Trip Overview

The average train between Middlesex and Manchester takes 2h 38m and the fastest train takes 2h 30m. The train runs at least 2 times per hour from Middlesex to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 38m
Duration: 189 mi
Distance: £81
Average price: Every 30 minutes
Frequency

Train

best

Take the train from London Euston to Manchester Piccadillytrain London Euston - Manchester Piccadilly

2h 45m

£65–109

Middlesex to Manchester train times

Trains run every 30 minutes between Middlesex and Manchester. The earliest departure is at 5:45 AM in the morning, and the last departure from Middlesex is at 9:32 PM which arrives into Manchester at 12:39 AM. All services require a transfer, and take on average 2h 38m. The schedules shown below are for the next available departures.

Departing Wednesday, October 28, 2026

8:02 PM → 10:45 PM
2h 43m • 1 change
8:32 PM → 11:07 PM
2h 35m • 1 change
9:17 PM → 11:48 PM
2h 31m • 1 change
9:32 PM → 12:39 AM
Arrives next day
3h 7m • 1 change

Departing Thursday, October 29, 2026

5:45 AM → 8:25 AM
2h 40m • 1 change
6:01 AM → 8:45 AM
2h 43m • 1 change
6:16 AM → 9:05 AM
2h 48m • 1 change
6:47 AM → 9:19 AM
2h 32m • 1 change
Show more

Departing Friday, October 30, 2026

5:45 AM → 8:25 AM
2h 40m • 1 change
6:01 AM → 8:45 AM
2h 43m • 1 change
6:16 AM → 9:05 AM
2h 48m • 1 change
6:47 AM → 9:19 AM
2h 32m • 1 change
Show more

Departing Saturday, October 31, 2026

5:47 AM → 8:44 AM
2h 57m • 1 change
6:17 AM → 9:05 AM
2h 48m • 1 change
6:47 AM → 9:19 AM
2h 32m • 1 change
7:02 AM → 9:44 AM
2h 42m • 1 change
Show more

Departing Sunday, November 1, 2026

7:19 AM → 10:55 AM
3h 36m • 1 change
7:47 AM → 11:01 AM
3h 14m • 1 change
8:47 AM → 12:05 PM
3h 18m • 1 change
9:47 AM → 1:02 PM
3h 15m • 1 change
Show more

Departing Monday, November 2, 2026

5:45 AM → 8:25 AM
2h 40m • 1 change
6:01 AM → 8:45 AM
2h 43m • 1 change
6:16 AM → 9:05 AM
2h 48m • 1 change
6:47 AM → 9:19 AM
2h 32m • 1 change
Show more

Departing Tuesday, November 3, 2026

5:45 AM → 8:25 AM
2h 40m • 1 change
6:01 AM → 8:45 AM
2h 43m • 1 change
6:16 AM → 9:05 AM
2h 48m • 1 change
6:47 AM → 9:19 AM
2h 32m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Middlesex to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Middlesex to Manchester trains

Find Transport to Manchester

Trip Overview

Train

Middlesex to Manchester train times

Departing Wednesday, October 28, 2026

8:02 PM → 10:45 PM

8:32 PM → 11:07 PM

9:17 PM → 11:48 PM

9:32 PM → 12:39 AMArrives next day

Departing Thursday, October 29, 2026

5:45 AM → 8:25 AM

6:01 AM → 8:45 AM

6:16 AM → 9:05 AM

6:47 AM → 9:19 AM

Departing Friday, October 30, 2026

5:45 AM → 8:25 AM

6:01 AM → 8:45 AM

6:16 AM → 9:05 AM

6:47 AM → 9:19 AM

Departing Saturday, October 31, 2026

5:47 AM → 8:44 AM

6:17 AM → 9:05 AM

6:47 AM → 9:19 AM

7:02 AM → 9:44 AM

Departing Sunday, November 1, 2026

7:19 AM → 10:55 AM

7:47 AM → 11:01 AM

8:47 AM → 12:05 PM

9:47 AM → 1:02 PM

Departing Monday, November 2, 2026

5:45 AM → 8:25 AM

6:01 AM → 8:45 AM

6:16 AM → 9:05 AM

6:47 AM → 9:19 AM

Departing Tuesday, November 3, 2026

5:45 AM → 8:25 AM

6:01 AM → 8:45 AM

6:16 AM → 9:05 AM

6:47 AM → 9:19 AM

Frequently asked questions

What companies run services between Middlesex, England and Manchester, England?

Train from London Euston to Manchester Piccadilly

Where to next?

Train trips from Middlesex

Train trips to Manchester

Alternative transport options

9:32 PM → 12:39 AM
Arrives next day