The average train between Mexborough and Manchester takes 2h 1m and the fastest train takes 1h 40m. There is a train service every few hours from Mexborough to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mexborough and Manchester. The earliest departure is at 6:18 AM in the morning, and the last departure from Mexborough is at 11:49 PM which arrives into Manchester at 4:32 AM. All services require a transfer, and take on average 2h 1m. The schedules shown below are for the next available departures.

1h 47m • 1 change

1h 49m • 1 change

1h 54m • 1 change

1h 50m • 1 change

1h 47m • 1 change

1h 49m • 1 change

1h 54m • 1 change

1h 50m • 1 change

1h 47m • 1 change

1h 49m • 1 change

1h 54m • 1 change

1h 50m • 1 change
Want to know about travelling from Mexborough to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mexborough to Manchester. However, there are services departing from Mexborough station and arriving at Manchester station via Sheffield. The journey, including transfers, takes approximately 2h 1m.
Mexborough to Manchester train services, operated by Northern Trains Limited, depart from Mexborough station.
Mexborough to Manchester train services, operated by Northern Trains Limited, arrive at Manchester Piccadilly station.
Book your Mexborough to Manchester train tickets online with Northern Trains Limited, TransPennine Express and East Midlands Railways.
The distance between Mexborough and Manchester is 62.5 km. The road distance is 86 km.
You can take a train from Mexborough to Manchester Piccadilly via Sheffield in around 1h 34m.