The average train between Mestre and Naples takes 6h 10m and the fastest train takes 5h 11m. The train service runs several times per day from Mestre to Naples. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Mestre and Naples. The earliest departure is at 7:17 AM in the morning, and the last departure from Mestre is at 6:17 PM which arrives into Naples at 7:12 AM. All services require a transfer, and take on average 6h 10m. The schedules shown below are for the next available departures.

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Want to know about travelling from Mestre to Naples? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mestre to Naples. However, there are services departing from Mestre station and arriving at Naples station via Roma Termini. The journey, including transfers, takes approximately 6h 10m.
Mestre to Naples train services, operated by ItaloTreno, depart from Venezia Mestre station.
Mestre to Naples train services, operated by ItaloTreno, arrive at Napoli station.
Book your Mestre to Naples train tickets online with ItaloTreno.
The distance between Mestre and Naples is 541.3 km. The road distance is 716 km.
You can take a train from Venezia Mestre to Napoli via Roma Termini in around 5h 10m.