The average train between Merseburg and Mannheim takes 4h 5m and the fastest train takes 3h 41m. The train service runs several times per day from Merseburg to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Merseburg and Mannheim. The earliest departure is at 7:57 AM in the morning, and the last departure from Merseburg is at 7:57 PM which arrives into Mannheim at 12:21 AM. All services require a transfer at Halle(Saale)Hbf and take an average of 4h 5m. The schedules shown below are for the next available departures.


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Want to know about travelling from Merseburg to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Merseburg to Mannheim. However, there are services departing from Merseburg station and arriving at Mannheim station via Frankfurt. The journey, including transfers, takes approximately 4h 5m.
Merseburg to Mannheim train services, operated by Deutsche Bahn Regio (DB Regional), depart from Halle(Saale)Hbf station.
Merseburg to Mannheim train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Book your Merseburg to Mannheim train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Merseburg and Mannheim is 324.4 km. The road distance is 439 km.
You can take a train from Merseburg Hbf to Mannheim, Hauptbahnhof via Halle(Saale)Hbf and Frankfurt in around 4h 31m.