The average train between Merseburg and Mannheim takes 5h 40m and the fastest train takes 5h 16m. The train service runs several times per day from Merseburg to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Merseburg and Mannheim. The earliest departure is at 4:28 AM at night, and the last departure from Merseburg is at 8:13 PM which arrives into Mannheim at 3:22 AM. All services require a transfer, and take on average 5h 40m. The schedules shown below are for the next available departures.

6h 27m • 1 change

5h 16m • 1 change

5h 16m • 1 change

5h 16m • 1 change

6h 27m • 1 change

5h 16m • 1 change

5h 16m • 1 change

5h 16m • 1 change

6h 27m • 1 change

5h 16m • 1 change

5h 16m • 1 change

5h 16m • 1 change

6h 27m • 1 change

5h 16m • 1 change

5h 16m • 1 change

5h 16m • 1 change

6h 27m • 1 change

5h 16m • 1 change

5h 16m • 1 change

5h 16m • 1 change

7h 1m • 1 change

5h 16m • 1 change

5h 16m • 1 change

5h 16m • 1 change
Want to know about travelling from Merseburg to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Merseburg to Mannheim. However, there are services departing from Merseburg station and arriving at Mannheim station via Erfurt Hbf. The journey, including transfers, takes approximately 5h 40m.
Merseburg to Mannheim train services, operated by ABELLIO Rail Mitteldeutschland GmbH, depart from Merseburg Hbf station.
Merseburg to Mannheim train services, operated by ABELLIO Rail Mitteldeutschland GmbH, arrive at Mannheim, Hauptbahnhof station.
Book your Merseburg to Mannheim train tickets online with ABELLIO Rail Mitteldeutschland GmbH and Deutsche Bahn Intercity (DB IC).
The distance between Merseburg and Mannheim is 324.4 km. The road distance is 427 km.
You can take a train from Merseburg Hbf to Mannheim, Hauptbahnhof via Erfurt Hbf in around 4h 52m.