The average train between Merseburg and Mainz takes 4h 37m and the fastest train takes 4h 13m. There is a train service every few hours from Merseburg to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Merseburg and Mainz. The earliest departure is at 4:28 AM at night, and the last departure from Merseburg is at 8:13 PM which arrives into Mainz at 12:52 AM. All services require a transfer at Erfurt Hbf and take an average of 4h 37m. The schedules shown below are for the next available departures.


4h 55m • 2 changes

5h 10m • 2 changes

4h 31m • 2 changes

4h 31m • 2 changes

4h 54m • 2 changes

4h 42m • 2 changes

5h 9m • 2 changes

4h 31m • 2 changes

4h 54m • 2 changes

4h 42m • 2 changes

5h 9m • 2 changes

4h 31m • 2 changesWant to know about travelling from Merseburg to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Merseburg to Mainz. However, there are services departing from Merseburg station and arriving at Mainz station via Erfurt Hbf. The journey, including transfers, takes approximately 4h 37m.
Merseburg to Mainz train services, operated by ABELLIO Rail Mitteldeutschland GmbH, depart from Merseburg Hbf station.
Merseburg to Mainz train services, operated by ABELLIO Rail Mitteldeutschland GmbH, arrive at Frankfurt station.
Book your Merseburg to Mainz train tickets online with ABELLIO Rail Mitteldeutschland GmbH, Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Merseburg and Mainz is 302.6 km. The road distance is 388 km.
You can take a train from Merseburg Hbf to Mainz, Römisches Theater via Erfurt Hbf and Frankfurt in around 4h 38m.