The average train between Mechelen and Lyon takes 4h 34m and the fastest train takes 4h 13m. The train service runs several times per day from Mechelen to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mechelen and Lyon. The earliest departure is at 1:37 AM at night, and the last departure from Mechelen is at 5:33 PM which arrives into Lyon at 9:59 PM. All services require a transfer, and take on average 4h 34m. The schedules shown below are for the next available departures.

4h 15m • 1 change

4h 13m • 1 change

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4h 30m • 1 change

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4h 14m • 1 change

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4h 15m • 1 change

4h 14m • 1 change

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4h 14m • 1 change
Want to know about travelling from Mechelen to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mechelen to Lyon. However, there are services departing from Mechelen station and arriving at Lyon station via Lyon Part Dieu. The journey, including transfers, takes approximately 4h 34m.
Mechelen to Lyon train services, operated by Belgian Railways (NMBS/SNCB), depart from Brussel-Zuid / Bruxelles-Midi station.
Mechelen to Lyon train services, operated by Belgian Railways (NMBS/SNCB), arrive at Lyon Part Dieu station.
Book your Mechelen to Lyon train tickets online with Belgian Railways (NMBS/SNCB) and TGV inOui.
The distance between Mechelen and Lyon is 587.4 km. The road distance is 774 km.
TGV inOui operates a train from Brussel-Zuid / Bruxelles-Midi to Lyon Part Dieu hourly. Tickets cost €160–270 and the journey takes 3h 53m.